Analysis of resistance-associated gene expression in docetaxel-resistant prostate cancer cells.

@article{Lee2017AnalysisOR,
  title={Analysis of resistance-associated gene expression in docetaxel-resistant prostate cancer cells.},
  author={Sangchul Lee and Kwangtaek Kim and Jin-Nyoung Ho and Hyunjin Jin and Seok-Soo Byun and Eunsik Lee},
  journal={Oncology letters},
  year={2017},
  volume={14 3},
  pages={3011-3018}
}
Docetaxel-based chemotherapy is the standard treatment for metastatic castration-resistant prostate cancer (CRPC). However, a number of patients with metastatic CRPC are refractory to docetaxel or develop docetaxel resistance. The underlying molecular mechanisms of docetaxel resistance remain unclear, which is a significant burden to the management of metastatic prostate cancer. In the present study, the differential gene expression between docetaxel-sensitive (PC3) and docetaxel-resistant… CONTINUE READING

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