Analysis of replication protein A (RPA) in human spermatogenesis.

@article{OliverBonet2007AnalysisOR,
  title={Analysis of replication protein A (RPA) in human spermatogenesis.},
  author={Mar{\'i}a Oliver-Bonet and Mercedes Campillo and Paul J. Turek and Eunae Ko and R. H. Martin},
  journal={Molecular human reproduction},
  year={2007},
  volume={13 12},
  pages={837-44}
}
Replication protein A (RPA) has been identified as a component of early recombination nodules. It is thought to stimulate homologous pairing and strand exchange reactions. The expression pattern of RPA in human spermatocytes has been analysed using immunocytogenetic techniques on testicular biopsies from adult male patients. What appears to be connecting RPA-filaments was observed between as yet unsynapsed homologous regions at early stages of zygotene. RPA foci were also observed in synaptic… CONTINUE READING

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