Analysis of repetitive element DNA methylation by MethyLight

@article{Weisenberger2005AnalysisOR,
  title={Analysis of repetitive element DNA methylation by MethyLight},
  author={Daniel J. Weisenberger and Mihaela Campan and Tiffany I. Long and Myungjin Kim and Christian B. Woods and Emerich S. Fiala and Melanie Ehrlich and Peter W. Laird},
  journal={Nucleic Acids Research},
  year={2005},
  volume={33},
  pages={6823 - 6836}
}
Repetitive elements represent a large portion of the human genome and contain much of the CpG methylation found in normal human postnatal somatic tissues. Loss of DNA methylation in these sequences might account for most of the global hypomethylation that characterizes a large percentage of human cancers that have been studied. There is widespread interest in correlating the genomic 5-methylcytosine content with clinical outcome, dietary history, lifestyle, etc. However, a high-throughput… CONTINUE READING

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