Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome
@article{Bos2009AnalysisOR, title={Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome}, author={David H. Bos and Chris Mayfield and D. J. Minchella}, journal={BMC Genomics}, year={2009}, volume={10}, pages={488 - 488} }
BackgroundNew chemotherapeutic agents against Schistosoma mansoni, an etiological agent of human schistosomiasis, are a priority due to the emerging drug resistance and the inability of current drug treatments to prevent reinfection. Proteases have been under scrutiny as targets of immunological or chemotherapeutic anti-Schistosoma agents because of their vital role in many stages of the parasitic life cycle. Function has been established for only a handful of identified S. mansoni proteases…
28 Citations
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