• DOI:10.1186/1471-2164-10-488
Corpus ID: 3218161

Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome

@article{Bos2009AnalysisOR,
  title={Analysis of regulatory protease sequences identified through bioinformatic data mining of the Schistosoma mansoni genome},
  author={D. H. Bos and Chris Mayfield and D. Minchella},
  journal={BMC Genomics},
  year={2009},
  volume={10},
  pages={488 - 488}
}

D. H. Bos, Chris Mayfield, D. Minchella

Published 2009

Medicine, Biology

BMC Genomics

BackgroundNew chemotherapeutic agents against Schistosoma mansoni, an etiological agent of human schistosomiasis, are a priority due to the emerging drug resistance and the inability of current drug treatments to prevent reinfection. Proteases have been under scrutiny as targets of immunological or chemotherapeutic anti-Schistosoma agents because of their vital role in many stages of the parasitic life cycle. Function has been established for only a handful of identified S. mansoni proteases… CONTINUE READING

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