Analysis of regulatory motifs within HPV transcripts.

@article{Cumming2005AnalysisOR,
  title={Analysis of regulatory motifs within HPV transcripts.},
  author={Sarah A Cumming and Sheila V Graham},
  journal={Methods in molecular medicine},
  year={2005},
  volume={119},
  pages={
          291-315
        }
}
  • Sarah A Cumming, Sheila V Graham
  • Published in Methods in molecular medicine 2005
  • Biology, Medicine
  • Papillomavirus late gene expression is highly dependent on host epithelial cell differentiation, such that capsid proteins are produced only in differentiating cells. Several papillomaviruses contain negative regulatory elements (NREs), that is, short regions of late transcripts that interact with host cellular RNA processing factors to prevent capsid protein synthesis in undifferentiated cells. In this chapter, the human papillomavirus (HPV)-16 NRE will be used as an example to show how cis… CONTINUE READING

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