Analysis of randomized and nonrandomized patients in clinical trials using the comprehensive cohort follow-up study design.

@article{Olschewski1992AnalysisOR,
  title={Analysis of randomized and nonrandomized patients in clinical trials using the comprehensive cohort follow-up study design.},
  author={M. Olschewski and Martin Schumacher and Kathryn B. Davis},
  journal={Controlled clinical trials},
  year={1992},
  volume={13 3},
  pages={226-39}
}
In clinical research, randomized trials are widely accepted as the definitive method of evaluating the efficacy of therapies. The random assignment of patients to their treatment ensures the internal validity of the comparison of new treatments with controls. An assessment of the external validity of trial results can best be achieved by comparing the study population to the population of patients who met the eligibility criteria but did not consent to randomization. A part of the data of the… CONTINUE READING

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