Analysis of quantitative trait loci in mice suggests a role of Enoph1 in stress reactivity.

@article{Barth2014AnalysisOQ,
  title={Analysis of quantitative trait loci in mice suggests a role of Enoph1 in stress reactivity.},
  author={Alexander Barth and Andras Bilkei-Gorz{\'o} and Eva Drews and David M. Otte and Amalia N Diaz-Lacava and Jeeva Varadarajulu and Christoph Wilhelm Turck and Thomas F. Wienker and Andreas Zimmer},
  journal={Journal of neurochemistry},
  year={2014},
  volume={128 6},
  pages={807-17}
}
Significant progress in elucidating the genetic etiology of anxiety and depression has been made during the last decade through a combination of human and animal studies. In this study, we aimed to discover genetic loci linked with anxiety as well as depression in order to reveal new candidate genes. Therefore, we initially tested the behavioral sensitivity of 543 F2 animals derived from an intercross of C57BL/6J and C3H/HeJ mice in paradigms for anxiety and depression. Next, all animals were… CONTINUE READING