Analysis of putative RNase sensitivity and protease insensitivity of demethylation activity in extracts from rat myoblasts.

@article{Swisher1998AnalysisOP,
  title={Analysis of putative RNase sensitivity and protease insensitivity of demethylation activity in extracts from rat myoblasts.},
  author={Jennifer F Swisher and Eyal Rand and Howard Cedar and A Marie Pyle},
  journal={Nucleic acids research},
  year={1998},
  volume={26 24},
  pages={5573-80}
}
The mechanism for demethylation of DNA in rat myoblasts has recently been studied using a new in vitro system that monitors demethylation in whole cell extracts. Previous investigations using this system had indicated that demethylation is resistant to conditions that are normally assumed to denature or digest proteins. Remarkably, it was reported that the… CONTINUE READING