Analysis of pulegone and its enanthiomeric distribution in mint-flavoured food products

@article{Siano2005AnalysisOP,
  title={Analysis of pulegone and its enanthiomeric distribution in mint-flavoured food products},
  author={Francesco Siano and Maurizio Catalfamo and Domenico Cautela and Luigi Servillo and Domenico Castaldo},
  journal={Food Additives \& Contaminants},
  year={2005},
  volume={22},
  pages={197 - 203}
}
A procedure for the extraction and determination of pulegone enanthiomers in mint essential oils and mint products (syrups, dried leaves, toothpaste, lozenges, candy and chewing-gum) was developed. The compounds were recovered from the food matrices by employing a simultaneous distillation–extraction (SDE) technique with a Likens–Nickerson apparatus using dichloromethane as an extraction solvent. The analyses were performed by capillary gas chromatography mass spectrometry (GC/MS). Experiments… 
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References

SHOWING 1-10 OF 24 REFERENCES
Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse.
Chiral compounds of essential oils XIV: Simultaneous stereoanalysis of buchu leaf oil compounds†
Multidimensional enantioselective gas chromatography, employing heart-cutting from a non-chiral precolumn onto a selectivity adjusted, modified cyclodextrin coated chiral main column, permits the
The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.
TLDR
Investigation with (R)-(+)-pulegone-d6 and 18O2 strongly indicate that menthofuran is formed by a sequence of reactions that involve: 1) oxidation of an allylic methyl group, 2) intramolecular cyclization to form a hemiketal, and 3) dehydration to form the furan.
Short term toxicity study in rats dosed with pulegone and menthol.
Metabolic disposition of a monoterpene ketone, piperitenone, in rats: evidence for the formation of a known toxin, p-cresol.
TLDR
A probable mechanism for the formation of p-cresol from piperitenone (I) via the intermediacy of metabolite III has been proposed.
Biochemical, histopathological and ultrastructural changes in rat liver induced by r‐( + )‐pulegone, a monoterpene ketone
TLDR
The time course profile of the hepatocytes after treatment with pulegone indicates that endoplasmic reticulum is the organelle most affected, following which other degenerative changes occur ultimately leading to cell death.
The genuineness of two mint essential oils
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