Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations

@article{Ho2012AnalysisOP,
  title={Analysis of prostate cancer association with four single-nucleotide polymorphisms from genome-wide studies and serum phyto-estrogen concentrations},
  author={Clement K M Ho and Lorna Halley and Jinxing Wei and Fouad K. Habib},
  journal={Prostate Cancer and Prostatic Diseases},
  year={2012},
  volume={15},
  pages={365-368}
}
Background:Both genetics and the environment are implicated as risk factors for prostate cancer (PCa). This population-based case–control study evaluated four single-nucleotide polymorphisms (SNPs) previously identified by genome-wide association studies to be associated with increased PCa susceptibility. Potential relationships between serum concentrations of phyto-estrogens and SNPs were also investigated.Methods:Four SNPs (rs10993994, rs2660753, rs1016343 and rs6983267) were genotyped in 247… CONTINUE READING
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