Analysis of pre- and postsynaptic activity in the frog semicircular canal following ototoxic insult: differential recovery of background and evoked afferent activity.

@article{Russo2009AnalysisOP,
  title={Analysis of pre- and postsynaptic activity in the frog semicircular canal following ototoxic insult: differential recovery of background and evoked afferent activity.},
  author={Giancarlo Russo and Daniela Calzi and Luciana Gioglio and Laura Botta and Manuela Polimeni and Giampiero Zucca and Marta Martini and Donatella Contini and Riccardo Fesce and Maria Lisa Rossi and Ivo Prigioni},
  journal={Neuroscience},
  year={2009},
  volume={163 4},
  pages={1327-39}
}
Frogs were treated with a single dose of gentamicin administered intraotically to produce severe degeneration of posterior semicircular canal hair cells and to evaluate the time course of functional damage and recovery both at pre- and postsynaptic level. In isolated canal preparations the endoampullar potential, which reflects the summed receptor… CONTINUE READING