Analysis of polymorphism in the protease and reverse transcriptase genes of HIV type 1 CRF02-AG subtypes from drug-naive patients from Saint-Etienne, France.

@article{Lawrence2006AnalysisOP,
  title={Analysis of polymorphism in the protease and reverse transcriptase genes of HIV type 1 CRF02-AG subtypes from drug-naive patients from Saint-Etienne, France.},
  author={Philip Lawrence and Marie-France Lutz and H{\'e}nia Saoudin and Anne Fr{\'e}sard and C{\'e}line Cazorla and Pascal Fascia and Sylvie Pillet and Bruno Pozzetto and Fr{\'e}d{\'e}ric R Lucht and Thomas Bourlet},
  journal={Journal of acquired immune deficiency syndromes},
  year={2006},
  volume={42 4},
  pages={396-404}
}
SUMMARY : The proportion of non-B HIV-1 variants is increasing in Western Europe. The impact of the high polymorphism in the protease and reverse transcriptase genes, as recently described for CRF02-AG isolates of African origin, on antiretroviral resistance is still disputed. We first examined the polymorphism of these genes in CRF02-AG strains recovered from drug-naive patients followed at the University Hospital of Saint-Etienne in France, most of these of French origin and harboring a… CONTINUE READING

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