Analysis of platelet abnormalities in uremia with and without Glanzmann's thrombasthenia.

@article{Nomura1994AnalysisOP,
  title={Analysis of platelet abnormalities in uremia with and without Glanzmann's thrombasthenia.},
  author={Shosaku Nomura and Kenjiro Hamamoto and T. Kawakatsu and Hirofumi Kido and Koichi Yamaguchi and Tsutomu Fukuroi and Motoyuki Suzuki and Mutsumasa Yanabu and Akira Shouzu and Mitsushige Nishikawa},
  journal={Nephron},
  year={1994},
  volume={68 4},
  pages={442-8}
}
Uremia causes a bleeding tendency associated with platelet dysfunction, and previous studies have shown abnormalities of platelet glycoprotein (GP) Ib or GPIIb/IIIa and a tendency for platelet activation in uremia. The present study compared the abnormalities of platelet function in uremia with (n = 1) or without (n = 18) associated Glanzmann's thrombasthenia. There was a significant difference between ristocetin-induced agglutination of platelets from the uremic patients without Glanzmann's… CONTINUE READING