Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model.

@article{Hu2002AnalysisOO,
  title={Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model.},
  author={Jiong Hu and Masaaki Takatoku and Stephanie E Sellers and Brian A Agricola and Mark E. Metzger and Robert E Donahue and Cynthia E Dunbar},
  journal={Human gene therapy},
  year={2002},
  volume={13 17},
  pages={2041-50}
}
Adult marrow-derived cells have been shown to contribute to various nonhematologic tissues and, conversely, primitive cells isolated from nonhematopoietic tissues have been shown to reconstitute hematopoiesis. Circulating endothelial progenitor cells (EPCs) have been reported to be at least partially donor derived after allogeneic bone marrow transplantation, and shown to contribute to neovascularization in murine ischemia models. However, it is unknown whether these EPCs are actually clonally… CONTINUE READING

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