Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum

@article{Gayen2006AnalysisOO,
  title={Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum},
  author={Kalyan Gayen and Kareenhalli V. Venkatesh},
  journal={BMC Bioinformatics},
  year={2006},
  volume={7},
  pages={445 - 445}
}
Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metabolite. The first step in this quantification is the enumeration of stoichiometries of all reactions occurring in a metabolic network. The structural details of the network in combination with experimentally observed accumulation rates of external metabolites can yield flux distribution at steady state. One such methodology for… CONTINUE READING

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View 9 Excerpts
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References

Publications referenced by this paper.
Showing 1-10 of 32 references

Identification of branch-point restrictions in microbial metabolism through metabolic flux balance analysis and local network perturbations

JJ Vallino
In PhD Thesis Massachusetts Institute of Technology, • 1991
View 7 Excerpts
Highly Influenced

Biochemical production capabilities of Escherichia coli.

Biotechnology and bioengineering • 1993
View 5 Excerpts
Highly Influenced

A method for the determination of flux in elementary modes, and its application to Lactobacillus rhamnosus

MG Poolman, KV Venkatesh, MK Pidcosk, DA Fell
Biotechnol Bioeng • 2004
View 1 Excerpt

Metabolic pathway analysis in biotechnology

S Schuster
Metabolic Engineering in the Post Genomic Era Wymondham , Horizon Scientific • 2004
View 1 Excerpt

[Metabolic flux analysis of L-valine fermentation in Corynebacterium glutamicum].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology • 2004
View 1 Excerpt

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