Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum

  title={Analysis of optimal phenotypic space using elementary modes as applied to Corynebacterium glutamicum},
  author={Kalyan Gayen and Kareenhalli V. Venkatesh},
  journal={BMC Bioinformatics},
  pages={445 - 445}
Quantification of the metabolic network of an organism offers insights into possible ways of developing mutant strain for better productivity of an extracellular metabolite. The first step in this quantification is the enumeration of stoichiometries of all reactions occurring in a metabolic network. The structural details of the network in combination with experimentally observed accumulation rates of external metabolites can yield flux distribution at steady state. One such methodology for… CONTINUE READING


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