Analysis of one million base pairs of Neanderthal DNA

@article{Green2006AnalysisOO,
  title={Analysis of one million base pairs of Neanderthal DNA},
  author={Richard E. Green and Johannes Krause and Susan E. Ptak and Adrian W. Briggs and Michael T. Ronan and Jan Fredrik Simons and Lei Du and Michael Wayland Egholm and Jonathan Rothberg and Maja Paunovi{\'c} and Svante P{\"a}{\"a}bo},
  journal={Nature},
  year={2006},
  volume={444},
  pages={330-336}
}
Neanderthals are the extinct hominid group most closely related to contemporary humans, so their genome offers a unique opportunity to identify genetic changes specific to anatomically fully modern humans. We have identified a 38,000-year-old Neanderthal fossil that is exceptionally free of contamination from modern human DNA. Direct high-throughput sequencing of a DNA extract from this fossil has thus far yielded over one million base pairs of hominoid nuclear DNA sequences. Comparison with… Expand
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