Analysis of non-crossover bivalents in pachytene cells from 10 normal men.

@article{Sun2006AnalysisON,
  title={Analysis of non-crossover bivalents in pachytene cells from 10 normal men.},
  author={Fei Sun and Mar{\'i}a Oliver-Bonet and Thomas Liehr and Heike Starke and Paul J. Turek and Evelyn Ko and Alfred Rademaker and R. H. Martin},
  journal={Human reproduction},
  year={2006},
  volume={21 9},
  pages={2335-9}
}
BACKGROUND Bivalents with no recombination foci (possible achiasmates) are unable to orient properly on the metaphase plate or to segregate chromosomes to daughter cells. Non-crossover bivalents are known to cause meiotic arrest in various organisms. METHODS Individual non-crossover bivalents were identified in 886 pachytene cells (19 492 bivalents) from testicular biopsies of 10 normal men. Fluorescence staining combined with centromere-specific multicolour fluorescence in situ hybridization… CONTINUE READING
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