Analysis of neuronal networks: a review of techniques for labeling axonal projections.

@article{Ralston1990AnalysisON,
  title={Analysis of neuronal networks: a review of techniques for labeling axonal projections.},
  author={Henry J Peter Ralston},
  journal={Journal of electron microscopy technique},
  year={1990},
  volume={15 4},
  pages={322-31}
}
In order to analyze connections between neurons in the vertebrate central nervous system, methods have been developed to label a given population of axons of known origin so that they can be differentiated from other, non-labeled structures. Three such methods are reviewed here: experimentally induced orthograde (Wallerian) degeneration, axon transport of radioactive proteins demonstrated by autoradiography, and axon transport of macromolecules that can be reacted histochemically to yield a… CONTINUE READING

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