Analysis of multiple loci can increase reliability of detection of fetal Y-chromosome DNA in maternal plasma.


OBJECTIVE Aiming to develop more reliable methods for determination of fetal gender from maternal plasma we compared three different systems of polymerase chain reaction (PCR) detection of Y-chromosome DNA. METHODS Cell-free DNA was isolated from 96 samples of maternal plasma and (1) amplified using AmpFLSTR-Identifiler (15 autosomal STR loci and… (More)
DOI: 10.1002/pd.1986


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