Analysis of monoamines in the cerebrospinal fluid of Chinese patients with Alzheimer's disease.

@article{Liu1991AnalysisOM,
  title={Analysis of monoamines in the cerebrospinal fluid of Chinese patients with Alzheimer's disease.},
  author={Hsiu-Chih Liu and Joseph C S Yang and Yi Fang Chang and Tian Yi Liu and C. W. Chi},
  journal={Annals of the New York Academy of Sciences},
  year={1991},
  volume={640},
  pages={215-8}
}
We have established HPLC assay conditions that could measure the levels of 14 monoamines and their metabolites simultaneously. Monoamine levels in cerebrospinal fluids of 12 Chinese patients with Alzheimer's disease were compared with those in samples from patients with benign prostate hyperplasia. Of the 14 monoamines and metabolites, only three were found to be present in all samples. Although the levels of 5-hydroxy-3-indoleacetic acid (HIAA) and homovanillic acid (HVA) in cerebrospinal… CONTINUE READING

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