Analysis of microsatellite instability in stool DNA of patients with colorectal cancer using denaturing high performance liquid chromatography.

@article{Lim2006AnalysisOM,
  title={Analysis of microsatellite instability in stool DNA of patients with colorectal cancer using denaturing high performance liquid chromatography.},
  author={Seok-Byung Lim and Seung-Yong Jeong and Il-Jin Kim and Dae Yong Kim and Kyung Hae Jung and Hee Jin Chang and Hyo Seong Choi and Dae Kyung Sohn and Hio Chung Kang and Yong Shin and Sang-Geun Jang and Jae-Hyun Park and J L Park},
  journal={World journal of gastroenterology},
  year={2006},
  volume={12 41},
  pages={6689-92}
}
AIM To evaluate the usefulness of denaturing high performance liquid chromatography (DHPLC) for analyzing microsatellite instability (MSI) status in stool DNA of patients with colorectal cancer. METHODS A total of 80 cancer tissues from patients with primary sporadic colorectal tumor (proximal cancer: 27, distal cancer: 53) and matched stool (which were employed for comparison with the tissues) were analyzed for MSI status in BAT 26. DNA samples extracted from stool were evaluated by nested… CONTINUE READING

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