Analysis of microsatellite instability in CRISPR/Cas9 editing mice.


Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR- associated (Cas) protein 9 system is a novel and powerful tool which is widely used for genome editing. CRISPR/Cas9 is RNA-guided and can lead to desired genomic modifications. However, whether the CRISPR/Cas9-mediated genome editing causes genomic alterations and genomic instability… (More)
DOI: 10.1016/j.mrfmmm.2017.02.003


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