Analysis of microRNA expression profile in specific pathogen-free chickens in response to reticuloendotheliosis virus infection


Reticuloendotheliosis virus (REV) is an avian retrovirus that causes immunosuppression, growth retardation, and oncogenesis in a variety of birds. REV infection is epidemic in many countries. In this study, we used high-throughput sequencing to identify microRNAs (miRNAs) associated with REV infection. A total of 88 differentially expressed miRNAs were… (More)
DOI: 10.1007/s00253-016-8060-0


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