Analysis of microRNA and gene networks in human chronic myelogenous leukemia.

  title={Analysis of microRNA and gene networks in human chronic myelogenous leukemia.},
  author={Kunhao Wang and Zhiwen Xu and Ning Wang and Ye Tian and Xin Sun and Yonggang Ma},
  journal={Molecular medicine reports},
  volume={13 1},
Molecular biologists have identified a number of genes and microRNAs (miRs) associated with chronic myelogenous leukemia (CML). However, their underlying mechanisms in CML remain unclear. In the present study, three regulatory networks of genes and miRs were constructed to elucidate the underlying mechanisms of CML. The first network was the experimentally validated network of miRs and genes. The second was the dysregulatory network of CML, consisting of dysregulated genes and miRs… CONTINUE READING
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