Analysis of methylation of 5'CpG island of P16、P15、P14 gene in bladder transitional cell carcinoma

@inproceedings{Dong2006AnalysisOM,
  title={Analysis of methylation of 5'CpG island of P16、P15、P14 gene in bladder transitional cell carcinoma},
  author={Gao Dong},
  year={2006}
}
Objective To evaluate methylation status of 5'CpG island of P16,P15,P14 gene and its clinical significance.Methods Methylation status of 5'CpG island of P16,P15,P14 gene were examined in 40 cases of BTCC and 8 cases of normal urothelium by means of methylation-specific PCR,χ~2 test was used to assess the relationship between the degree of methylation versus tumor grade and stage.Results The rate of methylation of P16,P15,P14 gene was found in27.5%,17.5%,35%cancer tissues and in 0 normal… CONTINUE READING