Analysis of medication use patterns:apparent overuse of antibiotics and underuse of prescription drugs for asthma, depression, and CHF.

  title={Analysis of medication use patterns:apparent overuse of antibiotics and underuse of prescription drugs for asthma, depression, and CHF.},
  author={Karen Gilberg and Marianne Laouri and Sally W. Wade and Sharon Isonaka},
  journal={Journal of managed care pharmacy : JMCP},
  volume={9 3},
OBJECTIVE To assess the appropriateness of prescription medication use based upon widely accepted treatment guidelines. METHODS We analyzed administrative claims for the period October 1, 1998, through September 20, 1999, supplied by 3 California health plans to determine medication use patterns for outpatient prescriptions. We compared these patterns to those expected in the presence of adherence to treatment guidelines. RESULTS During the study period, only 27.5% of antidepressant users… 

Antibiotic use in children who have asthma: results of retrospective database analysis.

It was demonstrated that pediatric asthmatic patients received significantly more antibiotic prescriptions than nonasthmatics for conditions caused by bacteria as well as for conditions more likely to be viral in origin.

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It is hypothesized that DM improves adherence to prescriptions more than the rate with which prescriptions are being filled, and more complex MPR- and LOG-based measures could be more appropriate for DM evaluation.

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Overuse of Antidepressant Drugs for the Treatment of Depression

Unless prescribing patterns change, any benefits from increasing access to antidepressants for those with severe depression will be accompanied by significant harms due to inappropriate prescribing in conditions, such as mild depression, where antidepressants are not indicated.

Improving antimicrobial use: longitudinal assessment of an antimicrobial team including a clinical pharmacist.

It is demonstrated that despite the long-term presence of an AMT, the proportion of antimicrobial episodes requiring intervention and the percentage of accepted recommendations remained constant over a 3-year period.

Effect of Feedback Letters to Physicians and Pharmacists on the Appropriate Use of Medication in the Treatment of Asthma

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Multiple drug intolerance syndrome: prevalence, clinical characteristics, and management.

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Antibiotic prescribing for children with colds, upper respiratory tract infections, and bronchitis.

Antibiotic prescribing for children diagnosed as having colds, URIs, and bronchitis, conditions that typically do not benefit from antibiotics, represents a substantial proportion of total antibiotic prescriptions to children in the United States each year.

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Regular therapy with inhaled corticosteroids can substantially reduce the risk of a readmission for asthma after only 15 d of use, which appears as the most likely explanation for the disappearance of the beneficial effect after 6 mo of regular therapy.

The Use of β-Agonists and the Risk of Death and near Death from Asthma

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Low dose inhaled corticosteroids and the prevention of death from asthma.

A nested case-control study in which subjects who died of asthma were matched with controls within the cohort according to the length of follow-up at the time of death of the case patient (the index date), the date of study entry, and the severity of asthma.

Principles of Appropriate Antibiotic Use for Acute Rhinosinusitis in Adults: Background

These principles present an argument for a conservative approach to use of antibiotics in patients with sinusitis-like symptoms, consistent with efforts to reduce antibiotic use for respiratory infections in ambulatory patients.


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Principles of Appropriate Antibiotic Use for Treatment of Nonspecific Upper Respiratory Tract Infections in Adults: Background

The goals of this paper are to provide evidence-based recommendations for when to apply the diagnosis of upper respiratory tract infection and when to consider antibiotic treatment of adults with an uncomplicated upper respiratory tracts infection.

Geographic variation in the treatment of acute myocardial infarction: the Cooperative Cardiovascular Project.

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Guidelines For The Diagnosis And Management Of Asthma

  • A. BergJ. Moy
  • Medicine
    The Journal of the American Board of Family Medicine
  • 1992
Patients with asthma can expect to control their symptoms, prevent most acute asthma exacerbations, maintain the activity levels they desire, and attain near normal lung function with use of guidelines for the diagnosis and treatment of asthma.

Overview of Randomized Trials of Angiotensin-Converting Enzyme Inhibitors on Mortality and Morbidity in Patients With Heart Failure

Total mortality and hospitalization for congestive heart failure are significantly reduced by ACE inhibitors with consistent effects in a broad range of patients.