Analysis of medication use patterns:apparent overuse of antibiotics and underuse of prescription drugs for asthma, depression, and CHF.

@article{Gilberg2003AnalysisOM,
  title={Analysis of medication use patterns:apparent overuse of antibiotics and underuse of prescription drugs for asthma, depression, and CHF.},
  author={Karen Gilberg and Marianne Laouri and Sally W. Wade and Sharon Isonaka},
  journal={Journal of managed care pharmacy : JMCP},
  year={2003},
  volume={9 3},
  pages={
          232-7
        }
}
OBJECTIVE To assess the appropriateness of prescription medication use based upon widely accepted treatment guidelines. METHODS We analyzed administrative claims for the period October 1, 1998, through September 20, 1999, supplied by 3 California health plans to determine medication use patterns for outpatient prescriptions. We compared these patterns to those expected in the presence of adherence to treatment guidelines. RESULTS During the study period, only 27.5% of antidepressant users… 
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57 Citations

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It is hypothesized that DM improves adherence to prescriptions more than the rate with which prescriptions are being filled, and more complex MPR- and LOG-based measures could be more appropriate for DM evaluation.
A retrospective cohort study of correlates of response to pharmacologic therapy for hyperlipidemia in members of a managed care organization.
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It is demonstrated that despite the long-term presence of an AMT, the proportion of antimicrobial episodes requiring intervention and the percentage of accepted recommendations remained constant over a 3-year period.
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Changes in clinical practice guidelines from 1970 to the present point to an important, but not often noticed, addition of secondary prevention of disease effects to the objectives of medical care.
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TLDR
Many costly asthma-related hospitalizations and emergency department visits are preventable, and chronic disease care can be shifted to the ambulatory setting, according to an update to the National Heart, Lung, and Blood Institute guidelines.
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TLDR
The results of this study suggest that a majority of members receive a medication covered by their health plan subsequent to rejection of a claim for a prescribed drug that is the target of a step-therapy edit.
Depression and drug utilization in an elderly population
TLDR
Depressed mood is associated with polypharmacy in the broad elderly population, however, when indexes of disease severity were considered, the association was lost, indicating that depression is a marker of the burden of disease and does not increase drug consumption per se.
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