Analysis of mass transport-limited binding kinetics in evanescent wave biosensors.

@article{Schuck1996AnalysisOM,
  title={Analysis of mass transport-limited binding kinetics in evanescent wave biosensors.},
  author={Peter Schuck and Allen P Minton},
  journal={Analytical biochemistry},
  year={1996},
  volume={240 2},
  pages={262-72}
}
It is shown that currently used methods for analyzing surface plasmon resonance or resonant mirror biosensor data do not adequately take into account the effects of mass transport on the kinetics of ligand association and dissociation. Conventional analyses may yield arbitrary apparent reaction rate constants lying between the mass transport rate constant and the true intrinsic chemical binding rate constants, depending on the choice of ligand concentrations used in the experiments. A new… CONTINUE READING

From This Paper

Topics from this paper.
49 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

Similar Papers

Loading similar papers…