Analysis of malachite green and metabolites in fish using liquid chromatography atmospheric pressure chemical ionization mass spectrometry.

@article{Doerge1998AnalysisOM,
  title={Analysis of malachite green and metabolites in fish using liquid chromatography atmospheric pressure chemical ionization mass spectrometry.},
  author={Daniel R. Doerge and Mona I. Churchwell and Theresa A Gehring and Yong Mei Pu and Steven M. Plakas},
  journal={Rapid communications in mass spectrometry : RCM},
  year={1998},
  volume={12 21},
  pages={1625-34}
}
Malachite green (MG), a traditional agent used in aquaculture, is structurally related to other carcinogenic triphenylmethane dyes. Although MG is not approved for use in aquaculture, its low cost and high efficacy make illicit use likely. We developed sensitive and specific methods for determination of MG and its principal metabolite, leucoMG (LMG), in edible fish tissues using isotope dilution liquid chromatography atmosphere pressure chemical ionization mass spectrometry. MG and LMG… CONTINUE READING