Analysis of lung cancer incidence in the nurses’ health and the health professionals’ follow-up studies using a multistage carcinogenesis model

@article{Meza2007AnalysisOL,
  title={Analysis of lung cancer incidence in the nurses’ health and the health professionals’ follow-up studies using a multistage carcinogenesis model},
  author={Rafael Meza and William D. Hazelton and Graham A. Colditz and Suresh H. Moolgavkar},
  journal={Cancer Causes & Control},
  year={2007},
  volume={19},
  pages={317-328}
}
We analyzed lung cancer incidence among non-smokers, continuing smokers, and ex-smokers in the Nurses Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS) using the two-stage clonal expansion (TSCE) model. Age-specific lung cancer incidence rates among non-smokers are identical in the two cohorts. Within the framework of the model, the main effect of cigarette smoke is on the promotion of partially altered cells on the pathway to cancer. Smoking-related promotion is somewhat… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Chapter 7: Description of MISCAN-lung, the Erasmus MC Lung Cancer microsimulation model for evaluating cancer control interventions.

Risk analysis : an official publication of the Society for Risk Analysis • 2012
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Lung cancer incidence in never smokers.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2007
View 1 Excerpt

Multistage carcinogenesis and lung cancer mortality in three cohorts.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2005
View 9 Excerpts

Are women more susceptible to lung cancer?

Journal of the National Cancer Institute • 2004
View 2 Excerpts

Variations in lung cancer risk among smokers.

Journal of the National Cancer Institute • 2003
View 1 Excerpt

Similar Papers

Loading similar papers…