Analysis of llicit and illicit drugs in waste, surface and lake water samples using large volume direct injection high performance liquid chromatography--electrospray tandem mass spectrometry (HPLC-MS/MS).

@article{Berset2010AnalysisOL,
  title={Analysis of llicit and illicit drugs in waste, surface and lake water samples using large volume direct injection high performance liquid chromatography--electrospray tandem mass spectrometry (HPLC-MS/MS).},
  author={J D Berset and Rudolf Brenneisen and Christoph Mathieu},
  journal={Chemosphere},
  year={2010},
  volume={81 7},
  pages={859-66}
}
Llicit and illicit drugs represent a recent group of emerging contaminants and have been found in the aquatic environment. A HPLC-MS/MS method was developed using direct injection (DI) of larger volumes and a polar endcapped reversed-phase (RP) column to measure drug components in water samples belonging to the cocaine group, opiates, amphetamine-like stimulants and metabolites thereof. After validation, including sensitivity, linearity, recovery, precision and matrix effect studies, most drugs… CONTINUE READING
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