Analysis of intimal proteoglycans in atherosclerosis-prone and atherosclerosis-resistant human arteries by mass spectrometry.

@article{Talusan2005AnalysisOI,
  title={Analysis of intimal proteoglycans in atherosclerosis-prone and atherosclerosis-resistant human arteries by mass spectrometry.},
  author={Paul Talusan and Shahinaz Bedri and Suping Yang and Taj M Kattapuram and Nilsa Silva and Peter J. Roughley and James Richard Stone},
  journal={Molecular & cellular proteomics : MCP},
  year={2005},
  volume={4 9},
  pages={
          1350-7
        }
}
The propensity to develop atherosclerosis varies markedly among different sites in the human vasculature. To determine a possible cause for such differences in atherosclerosis susceptibility, a proteomics-based approach was used to assess the extracellular proteoglycan core protein composition of intimal hyperplasia from both the atherosclerosis-prone internal carotid artery and the atherosclerosis-resistant internal thoracic artery. The intimal proteoglycan composition in these… CONTINUE READING

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