Analysis of integrin functions in peri-implantation embryos, hematopoietic system, and skin.

@article{Montaez2007AnalysisOI,
  title={Analysis of integrin functions in peri-implantation embryos, hematopoietic system, and skin.},
  author={Eloi Monta{\~n}ez and Aleksandra Piwko-Czuchra and Martina Bauer and Shaohua Li and Peter D Yurchenco and Reinhard F{\"a}ssler},
  journal={Methods in enzymology},
  year={2007},
  volume={426},
  pages={239-89}
}
Integrins mediate cell adhesion, permit traction forces important for cell migration, and cross-talk with growth factor receptors to regulate cell proliferation, cell survival, and cell differentiation. The plethora of functions explains their central role for development and disease. The progress in mouse genetics and the ease with which the mouse genome can be manipulated enormously contributed to our understanding of how integrins exert their functions at the molecular level. In the present… CONTINUE READING
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