Analysis of immunological responses in psoriatic lesions: (1) immunopathological studies on psoriatic lesions.

@article{Kaneko1980AnalysisOI,
  title={Analysis of immunological responses in psoriatic lesions: (1) immunopathological studies on psoriatic lesions.},
  author={Fumio Kaneko and H Gushiken and Ikuro Kawagishi and Yoshio Miura and Koichi Kobayashi and Tetsuo Konno},
  journal={The Journal of investigative dermatology},
  year={1980},
  volume={75 5},
  pages={436-9}
}
In order to understand immunological responses in psoriatic lesions, immunofluorescent findings have been compared in early psoriatic lesions and fully developed plaque lesions. IgG and IgA were detected as the main antibodies in the horny layer by immunohistology. The IgA at the site of leukocyte accumulation in the horny layer seemed to be associated with secretory component (S-component) and joining chian. Regarding complement, the alternate pathway might be related to the immune reaction as… CONTINUE READING