Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment

Abstract

Gene expression during development and differentiation is regulated in a cell- and stage-specific manner by complex networks of intergenic and intragenic cis-regulatory elements whose numbers and representation in the genome far exceed those of structural genes. Using chromosome conformation capture, it is now possible to analyze in detail the interaction… (More)
DOI: 10.1038/ng.2871

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