Analysis of human synovial and bone marrow mesenchymal stem cells in relation to heat-inactivation of autologous and fetal bovine serums

@inproceedings{Nimura2010AnalysisOH,
  title={Analysis of human synovial and bone marrow mesenchymal stem cells in relation to heat-inactivation of autologous and fetal bovine serums},
  author={Akimoto Nimura and Takeshi Muneta and Koji Otabe and Hideyuki Koga and Young-Jin Ju and Tomoyuki Mochizuki and Koji Suzuki and Ichiro Sekiya},
  booktitle={BMC musculoskeletal disorders},
  year={2010}
}
BACKGROUND Though sera are essential for Mesenchymal stem cells (MSCs), the effect of heat-inactivation remains unknown. Autologous human serum is recommended for clinical use; however, it is unclear whether differentiation potentials are maintained. To examine whether heat-inactivation of serum affected the proliferation and whether autologous human serum influenced their multipotentiality. METHODS After whole blood collection, human synovium and bone marrow were harvested. Nucleated cells… CONTINUE READING