Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components.

@article{Urso2006AnalysisOH,
  title={Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components.},
  author={Maria L Urso and Angus G. Scrimgeour and Yi-Wen Chen and Paul Daniel Thompson and Priscilla M. Clarkson},
  journal={Journal of applied physiology},
  year={2006},
  volume={101 4},
  pages={1136-48}
}
We examined the effects of 48 h of knee immobilization on alterations in mRNA and protein in human skeletal muscle. We hypothesized that 48 h of immobilization would increase gene expression and respective protein products for ubiquitin-proteasome pathway (UPP) components. Also, we used microarray analysis to identify novel pathways. Biopsies were taken… CONTINUE READING