Analysis of human plasma proteins: a focus on sample collection and separation using free-flow electrophoresis

@article{Nissum2008AnalysisOH,
  title={Analysis of human plasma proteins: a focus on sample collection and separation using free-flow electrophoresis},
  author={Mikkel Nissum and A. F. L. Foucher},
  journal={Expert Review of Proteomics},
  year={2008},
  volume={5},
  pages={571 - 587}
}
Due to ease of accessibility, plasma has become the sample of choice for proteomics studies directed towards biomarker discovery intended for use in diagnostics, prognostics and even in theranostics. The result of these extensive efforts is a long list of potential biomarkers, very few of which have led to clinical utility. Why have so many potential biomarkers failed validation? Herein, we address certain issues encountered, which complicate biomarker discovery efforts originating from plasma… 
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