Analysis of human antibodies to erythrocyte binding antigen 175 of Plasmodium falciparum.

@article{Okenu2000AnalysisOH,
  title={Analysis of human antibodies to erythrocyte binding antigen 175 of Plasmodium falciparum.},
  author={Daniel M. N. Okenu and Eleanor M. Riley and Quentin D. Bickle and Phillip U. Agomo and Arnoldo Barbosa and Jerry Daugherty and David E. Lanar and David J Conway},
  journal={Infection and immunity},
  year={2000},
  volume={68 10},
  pages={5559-66}
}
Invasion of human erythrocytes by Plasmodium falciparum merozoites is a multistep process. For many strains of the parasite, part of this process requires that the erythrocyte binding antigen 175 (EBA-175) of the merozoite binds to sialic acid residues of glycophorin A on the erythrocyte surface, a receptor-ligand interaction which represents a potential target for inhibition by antibodies. This study characterizes the reactivity of naturally acquired human antibodies with four recombinant… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

Similar Papers

Loading similar papers…