Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: evidence for orthologous genes.

@article{Shannon1998AnalysisOH,
  title={Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: evidence for orthologous genes.},
  author={Mark Shannon and Lisa Stubbs},
  journal={Genomics},
  year={1998},
  volume={49 1},
  pages={112-21}
}
Genetic and physical mapping studies indicate that hundreds of zinc-finger (ZNF)-containing genes populate the human genome and that many of these genes are arranged in familial clusters. However, the extent to which these tandemly arrayed families are conserved among mammalian species is largely unknown. In a previous study, we identified a conserved cluster of Kruppel-associated box (KRAB)-containing ZNF genes located near the XRCC1 gene in human chromosome 19q13.2 and mouse chromosome 7 and… CONTINUE READING