Analysis of growth rate effects on productivity of recombinant Escherichia coli populations using molecular mechanism models.

Abstract

The influence of growth rate on Escherichia coli plasmid content and expression of a cloned-gene product has been described by a mathematical model based upon the molecular mechanism of lambdadv plasmid replication and known relationships between growth rate and transcription and translation activities of the host cell. The model simulates correctly… (More)

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@article{Lee1984AnalysisOG, title={Analysis of growth rate effects on productivity of recombinant Escherichia coli populations using molecular mechanism models.}, author={Sun Bok Lee and James E. Bailey}, journal={Biotechnology and bioengineering}, year={1984}, volume={26 1}, pages={66-73} }