Analysis of granulysin-mediated cytotoxicity in peripheral blood of patients with psoriatic arthritis

@article{Massari2011AnalysisOG,
  title={Analysis of granulysin-mediated cytotoxicity in peripheral blood of patients with psoriatic arthritis},
  author={Dra{\vz}en Massari and Larisa Prpi{\'c}-Massari and Tatjana Kehler and Marija Ka{\vs}telan and Bo{\vz}idar {\'C}urkovi{\'c} and Viktor Per{\vs}i{\'c} and Alen Ru{\vz}i{\'c} and Gordana Laskarin},
  journal={Rheumatology International},
  year={2011},
  volume={32},
  pages={2777-2784}
}
The objective of the present study was to investigate possible changes in granulysin (GNLY)-mediated cytotoxicity of peripheral blood lymphocytes in psoriatic arthritis (PsA) patients with respect to different phases of the disease. We prospectively enrolled 25 PsA patients in the active phase, 26 PsA patients in remission and 24 healthy controls. The simultaneous detection of intracellular GNLY and cell surface antigens (CD3 and CD56) was performed with flow cytometry. GNLY apoptotic protein… CONTINUE READING
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