Analysis of glutathione S-transferase genes polymorphisms and the risk of schizophrenia in a sample of Iranian population.

@article{Kashani2011AnalysisOG,
  title={Analysis of glutathione S-transferase genes polymorphisms and the risk of schizophrenia in a sample of Iranian population.},
  author={Farah Lotfi Kashani and Dor Mohammad Kordi-Tamandani and Roya Sahranavard and Mohammad Esmaeil Fazl Hashemi and Farzaneh Kordi-Tamandani and Adam Torkamanzehi},
  journal={Neuron glia biology},
  year={2011},
  volume={7 2-4},
  pages={199-203}
}
Glutathione S-transferases (GSTs) are major intracellular antioxidants, which, impaired in their function, are involved in the progress of schizophrenia (SCZ). The aim of this case-control study was to investigate the association between the polymorphism of glutathione S-transferases M1 (GSTM1), T1 (GSTT1), the glutathione S-transferase P1 gene (GSTP1) and SCZ. We isolated genomic DNA from peripheral blood of 93 individuals with SCZ and 99 healthy control subjects' genotypes analyzing them for… CONTINUE READING
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