Analysis of gene expression patterns of ovarian cancer cell lines with different metastatic potentials.

@article{Bai2006AnalysisOG,
  title={Analysis of gene expression patterns of ovarian cancer cell lines with different metastatic potentials.},
  author={Feihu Bai and Jinbo Feng and Yuan Cheng and Jie Shi and Ruojing Yang and Heng Cui},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  year={2006},
  volume={16 1},
  pages={202-9}
}
The objective of this study was to investigate the key genetic changes and molecular mechanisms in the process of invasion and metastasis of human epithelial ovarian cancers. The in vitro invasion assay was used to further testify that the human epithelial ovarian cancer cell line SKOV3.ip1 is more invasive and metastatic compared with its parental line SKOV3. A total of 17,000 human genome complementary DNA microarrays were used to compare the gene expression patterns of the two cell lines… CONTINUE READING