Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis.

@article{Darby2012AnalysisOG,
  title={Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis.},
  author={Alistair C Darby and Stuart D. Armstrong and Germanus Soh Bah and Gaganjot Kaur and Margaret A. Hughes and Suzanne Mahlburg Kay and Pia Koldkj{\ae}r and Lucille Rainbow and Alan Radford and Mark L. Blaxter and Vincent N. Tanya and Alexander John. Trees and Richard Cordaux and Jonathan M. Wastling and Benjamin L. Makepeace},
  journal={Genome research},
  year={2012},
  volume={22 12},
  pages={
          2467-77
        }
}
The α-proteobacterium Wolbachia is probably the most prevalent, vertically transmitted symbiont on Earth. In contrast with its wide distribution in arthropods, Wolbachia is restricted to one family of animal-parasitic nematodes, the Onchocercidae. This includes filarial pathogens such as Onchocerca volvulus, the cause of human onchocerciasis, or river blindness. The symbiosis between filariae and Wolbachia is obligate, although the basis of this dependency is not fully understood. Previous… CONTINUE READING

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