Analysis of functional domains of a GC box-binding protein, BTEB.

  title={Analysis of functional domains of a GC box-binding protein, BTEB.},
  author={Atsushi Kobayashi and Kazuhiro Sogawa and Hiroaki Imataka and Yoshiaki Fujii-Kuriyama},
  journal={Journal of biochemistry},
  volume={117 1},
BTEB is a small GC box-binding protein containing three contiguous zinc finger structures in the C-terminal region of the molecule, and activates or represses the transcription of genes with the GC box sequence in the promoter, depending on the repetitiveness of the GC box sequence [Imataka et al. (1992) EMBO J. 11, 3663-3671]. We have analyzed functional domains of BTEB in a transient expression system using Y-1 cells (a mouse adrenal cortex cell line). BTEB contained two regions responsible… CONTINUE READING

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