Analysis of factors predictive of survival based on 49 patients with systemic Wegener's granulomatosis and prospective follow-up.

@article{Mahr2001AnalysisOF,
  title={Analysis of factors predictive of survival based on 49 patients with systemic Wegener's granulomatosis and prospective follow-up.},
  author={Alfred Mahr and Thomas Girard and Rachid Agher and Lo{\"i}c Guillevin},
  journal={Rheumatology},
  year={2001},
  volume={40 5},
  pages={492-8}
}
OBJECTIVES This prospective study attempted to determine factors predictive of survival in systemic Wegener's granulomatosis (WG) based on 49 patients. Patients and methods. All patients had previously untreated systemic WG. Treatment was with oral or pulse cyclophosphamide plus corticosteroids. Univariate and multivariate analyses of survival were performed using 13 parameters evaluated at diagnosis. RESULTS The mortality rate was 37% during a mean follow-up period of 1.9 yr. Among the 13… CONTINUE READING

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