Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity.

@article{Ohnmacht2007AnalysisOE,
  title={Analysis of eosinophil turnover in vivo reveals their active recruitment to and prolonged survival in the peritoneal cavity.},
  author={Caspar Ohnmacht and Andrea Pullner and Nico Van Rooijen and David Voehringer},
  journal={Journal of immunology},
  year={2007},
  volume={179 7},
  pages={4766-74}
}
Eosinophils are potent effector cells associated with allergic inflammation and parasite infections. However, limited information exists about their turnover, migration, and survival in vivo. To address these important questions, we determined murine eosinophil turnover under steady state and inflammatory conditions by flow cytometric analysis of BrdU incorporation and analyzed their migration pattern and survival in different tissues after adoptive transfer into recipient mice. In naive mice… CONTINUE READING
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