Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry.

@article{Vanderford2003AnalysisOE,
  title={Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry.},
  author={Brett J Vanderford and Rebecca A Pearson and David J Rexing and Shane A. Snyder},
  journal={Analytical chemistry},
  year={2003},
  volume={75 22},
  pages={6265-74}
}
A method has been developed for the trace analysis of 27 compounds from a diverse group of pharmaceuticals, steroids, pesticides, and personal care products. The method employs solid-phase extraction (SPE) and liquid chromatography/tandem mass spectrometry (LC/MS/MS), using electrospray ionization (ESI) in both positive and negative modes and atmospheric pressure chemical ionization in positive mode. Unlike many previous methods, a single SPE procedure using 1 L of water coupled to a simple LC… CONTINUE READING
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