Analysis of effect of congenic mice on the gene expression under genomic background of BALB/c mice


Background Interleukin 1 (IL-1) is a major contributor to the development of immune-mediated arthritis. BALB/c mice that are homozygous for the deficiency (BALB/c) spontaneously develop joint-specific inflammation that resembles human rheumatoid arthritis [1]. To understand the role of genetic factors involved in the development of spontaneous arthritis… (More)
DOI: 10.1186/1471-2105-15-S10-P10


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