Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies.

@article{Hurwitz2013AnalysisOE,
  title={Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies.},
  author={Herbert I. Hurwitz and Pamela Sylvia Douglas and John Paul Middleton and George W. Sledge and David H. Johnson and David A Reardon and Dafeng Chen and Oliver Rosen},
  journal={The oncologist},
  year={2013},
  volume={18 3},
  pages={273-80}
}
BACKGROUND Hypertension is associated with antivascular endothelial growth factor treatment, but the clinical implications of hypertension are uncertain. To assess the prognostic and predictive value of bevacizumab-related hypertension, a comprehensive analysis of whether hypertension and efficacy outcomes are associated was conducted on seven company-sponsored placebo-controlled phase III studies of bevacizumab. METHODS Patient-specific data were available from 6,486 patients with metastatic… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Similar Papers

Loading similar papers…